N. El Khatib1, S. Genieys1, M. Zine2, and V. Volpert1
1Institut Camille Jordan, Université Claude Bernard, Lyon, France
2Département Maths & Informatique, Ecole Centrale de Lyon, Lyon, France
The development of atherosclerosis leads to the formation of an atheroma plaque which takes place in the artery. This plaque is composed of two parts: a lipid deposit and a fibrous cap. The fibrous cap covers the lipid deposit and isolates it from the blood flow. The blood flow that circulates in the artery modifies the geometry of the atheroma plaque and can cause dangerous effects, such as a ...
R. Said, R. Cotton, P. Young, A. Datta, M. Elwassif , and M. Bikson
 Simpleware Ltd, Exeter, Devon, UK
 Department of Biomedical Eng., The City College of New York, New York, NY, USA
This paper will discuss the comprehensive solution adopted for converting the 3D digital/medical images directly into the computational model. The workflow using Simpleware Software – ScanIP and + ScanFE – will be illustrated including the option for directly exporting fully compatible models to COMSOL Multiphysics. The extra functionality that allows introduction, positioning and ...
A. Eed Olamat, U. Hofmann, B. Pohl, and N. Nkemasong
University of Lübeck, Institute for Signal Processing, Lübeck, Germany
In order to investigate the implantation of microprobes into brain tissue, we developed a finite-element and a physical model to replace real biological tissue for mechanical testing. Penetrating forces of a tungsten indenter into a layered structure was investigated with different indentation speeds. Numerical and physical model are in good correspondence to each other and reproduce measured ...
The Effect of Cartilaginous Rings on Deposition by Convection, Brownian Diffusion and Electrostatics
Luleå University of Technology, Luleå, Sweden
This paper presents a numerical study of the deposition of spherical charged nanoparticles caused by convection and Brownian diffusion in a pipe with a cartilaginous ring structure. The model is supposed to describe deposition of charged particles in the upper generations of the tracheobronchial tree of the human lung. The upper airways are characterized by a certain wall structure called ...
Istituto Superiore di Osteopatia, Milan, Italy
The concept of cranial Primary Respiratory Mechanism (MRP) is used by osteopathic practitioners to explain the perceptual characteristics arising from the clinical palpation approach of the human skull. The theoretical apparatus and the same MRP existence is always element of controversy among the scientific community. The results arising from this study highlight the intrinsic capability of the ...
Numerical Simulation of the Functional Electromagnetic Stimulation of the Human Femoral Bone using COMSOL
Y. Haba, W. Kröger, H. Ewald, R. Souffrant, W. Mittelmeier, and R. Bader
Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, University of Rostock, Rostock, Germany
Institute of General Electrical Engineering, University of Rostock, Rostock, Germany
In the present study we determined the relative conductivities and permittivities of fresh cortical and cancellous bone measuring human femoral heads in different slices of 1 mm thickness. The identified conductivities of human trabecular bone are used for the electromagnetic field simulation by means of COMSOL using a Micro-Computed Tomography (Micro-CT) model. The calculated model depends on a ...
A. Jeremic, and A. Atalla
McMaster University, Hamilton, ON, Canada
In this paper, we develop a mathematical model to simulate the movement of bacteria into and within a capillary segment. Also, we model the transportation through capillary walls by means of anisotropic diffusivity that depends on the pressure difference across the capillary walls. By solving the model using COMSOL, it was possible to predict the concentration of bacteria at points within the ...
Search for a Suitable Numerical Model for Electrical Stimulation: from the Electric Double Layer to Electrokinetics, Confrontation with Impedance Measurements
P. Pham, R. Scapolan, C. Rubeck, and F. Dupont
CEA-LETI-MINATEC, Grenoble, France
Electrical Stimulation is widely used today for Deep Brain Stimulation treatments and retinal prostheses. The Electrical Double Layer formed at the interface between the electrode surface and the extracellular medium is considered thru the linear Helmholtz model and the nonlinear more realistic modified Poisson Boltzmann model. These different models, solved using COMSOL Multiphysics, are ...
M.S. Yeoman, A. Cizinauskas, C. Lowry, G. Vincent, S. Collins, D. Simpson
Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
Corin Group, Cirencester, United Kingdom
Imoprhics, Manchester, United Kingdom
Bone resorption around hip stems, in particular periprosthetic bone loss, is a common observation post-operatively. A number of factors influence the amount of bone loss over time and the mechanical environment following total hip replacement (THR) is important. Conventional long stem prostheses have been shown to transfer loads distally, resulting in bone loss of the proximal femur. More ...
O. Henao, V. Gómez, I. De la Pava, J. Sánchez
Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia
Electroporation is an increase of the cell membrane permeability due to the formation of aqueous pores in it when the cell is under the influence of an intense electric field . The formation of such pores in the membrane can be used to enhance the uptake of chemotherapeutic drugs into the cell in a cancer treatment known as electrochemotherapy . In some cases the direct experimental ...