Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Modeling of the Impact of Blood Vessels Flow on the Temperature Distribution During Focused Ultrasound Exposure

K.C.P. Li, B.E. O'Neill, and E. Sassaroli
Methodist Hospital Research Institute, Houston, TX, USA

Focused ultrasound systems guided by magnetic resonance imaging (MRI) and thermometry have recently made possible the non-invasive thermal ablation of benign tumors such as uterine fibroids in clinical practice. Much more work is however required in order to make this technology available for the treatment of other forms of cancer. One of the major difficulties is associated with the presence of ...

Studies of Lead Free Piezo-Electric Materials Based Ultrasonic MEMS Model for Bio sensor

P. Pattanaik[1], S. K. Kamilla[1], D. P. Das[2], S. K. Pradhan[3]
[1]MEMS Design Center, Institute of Technical Education & Research (ITER), Sikhya ‘O’ Anushandhan University, Bhubaneswar, Odisha, India
[2]Process Engineering and Instrumentation Lab, Institute of Minerals and Materials Technology (IMMT), Bhubaneswar, Odisha, India
[3]Dept of ECE, Hi-Tech Institute of Technology, Khurda, Odisha, India

This paper describes the design of an ultrasonic transducer using different lead free piezo-electric materials and evaluates their performance with different glucose levels in the human blood. COMSOL Multiphysics 4.2a was used for the simulation study using 2D axis symmetric model of piezoelectric transducer which was designed with lead free piezoelectric materials such as Barium Sodium Niobate ...

Actively Controlled Ionic Current Gating In Nanopores

G. Zhang[1], S. Bearden[1]
[1]Clemson University, Clemson, SC, USA

It is necessary to understand and control nanopore behavior in order to develop biosensors for a variety of applications including DNA sequencing. The fluidics of nanopore devices we fabricated exhibits a range of interesting phenomena, such as enhanced conductance and current rectification. By electrically biasing nanopores, we were able to actively control the nanopore conductance in real time ...

Effect of Permeability Diminution in Nutrient Diffusion in Intervertebral Disc

M. A. Chetoui [1], O. Boiron [2], A. Dogui [3], V. Deplano [2],
[1] Université de Monastir, Ecole Nationale D'ingénieurs de Monastir; Ecole centrale Marseille, Marseille, France
[2] Aix-Marseille Université, CNRS, Ecole Centrale, Marseille, France
[3] Université de Monastir, Ecole Nationale D'ingénieurs de Monastir, Marseille, France

Intervertebral discs (IVD) are fibro-cartilages situated between vertebrae providing their joint flexibility. They play a major role in the transmission and absorption of load through the spine. The disc can undergo progressive structural and quantitative changes in its composition and morphology related to mechanical load applied to the spine which can lead to disc degeneration; this disease is ...

Simulations of Microelectrode and Neuron Interfaces Enable Long-Term and High Fidelity Recordings

P. Wijdenes [1], H. Ali [2], N. Syed [3], C. Dalton [2],
[1] Centre for Bioengineering Research and Education, University of Calgary, Calgary, AB, Canada
[2] Department of Electrical and Computer Engineering, Schulich School of Engineering, University of Calgary, Calgary, AB, Canada
[3] Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada

Our inability to record single cell activity with high resolution over a long period of time precludes fundamental understanding of nervous system functions, both under normal and pathological conditions. While the fabrication of current micro- and nano-electrodes has advanced our capabilities to perform long-term recordings, this has been at the expense of signal resolution due to low sealing ...

Understanding the Role of Nanomaterials in DNA Biosensors Through Finite Element Analysis

J. C. Kumaradas[1], A. Zhang[2], Y. D. Davletshin[1]
[1]Ryerson University, Toronto, ON, Canada
[2]University of Waterloo, Waterloo, ON, Canada

Tremendous progress is being made in the integration of nanoparticles into micro-analytical systems for biosensing. These materials are shown to enhance the analyte capture capability of biosensing platforms. We have implemented a computational model that considers the sensor’s geometry, size, analyte concentration and type to predict the number of nucleic acid molecules captured by ...

Design and Strain Analysis of Artificial Femoral Head and Stem

N. M. Sundaram[1], M. Sneha[1], A. Kandaswamy[1], R. Nithya[2]
[1]PSG College of Technology, Coimbatore, Tamil Nadu, India
[2]Dr. N.G.P. Institute of Technology, Coimbatore, Tamil Nadu, India

The majority of elderly patients are subjected to hip bone replacement due to dislocation of bone, mechanical failure and infection. The life time of the implant varies from patient to patient depending on their daily physical activity. Once the implant fails, re-operation of hip bone replacement is performed. In United States, there are approximately 18 revision hip replacements performed for ...

Generation of Lofted NURBS Curves for 3D Model Generation with COMSOL Multiphysics®

R.T. Hart[1]
[1]Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA

A key challenge to finding quantitative solutions to biological problems is to model the complex 3D geometry of naturally occurring structures. Model generation often starts from serial sections from CT or MRI scans, confocal microscopy, or physical sectioning. In addition, prior to V4 of COMSOL Multiphysics®, there was a "loft" command to allow construction of 3D models from serial sections ...

Multiphysics Modeling of a Grain Storage Chamber - new

P. Guha[1], P. Sharma[1], V. Malhotra[1], S. Mishra[1]
[1]CSIR - Central Scientific Instruments Organisation, Chandigarh, India

Proper storage of grains depends on minimizing attacks of insects, fungi, mites, etc. Development of such pests can be controlled by controlling the temperature of the storage chamber. Hence, before designing grain storage chambers, mathematical modeling and numerical simulations should be performed to predict the temperature distributions. Changes in storage temperature may occur due to several ...

Microvascular Dysfunction in PAD Patients - new

K. Cluff[1], H. Mehraein[1], B. Jayakumar[2]
[1]Department of Bioengineering, Wichita State University, Wichita, KS, USA
[2]Department of Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA

Background: Peripheral arterial disease (PAD) is characterized by atherosclerotic blockages of the arteries supplying the lower extremities, which cause a progressive accumulation of ischemic injury to the skeletal muscles of the lower limbs. Despite revascularization treatment intervention some PAD patients require follow up secondary treatment due to a continued decline in limb function, ...