K. Gladine , J. Soons , J. Dirckx 
 University of Antwerp, Belgium
The ear doesn’t solely listen but it also speaks. Sounds formed in the inner ear which are measurable in the outer ear are called Otoacoustic emissions (OAEs). Some claim these are produced by the outer hair cells (OHCs), the amplifiers in the inner ear. Our hypothesis is that the OHCs only amplify distortion products (DPs) but do not produce them.
A. Gerisch, S. Tiburtius, Q. Grimal, and K. Raum
Technische Universität Darmstadt, Darmstadt, Germany
Laboratoire d’Imagerie Paramétrique, UPMC, Paris, France
Julius Wolff Institut & Berlin-Brandenburg School for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany
Musculoskeletal mineralized tissues (MMTs), e.g. bone, are hierarchical composite materials. Their effective elastic properties at different scales are of interest for computational studies of the MMT’s response to mechanical loading but also to realistically simulate implant osseointegration. We combine multi-scale and multi-modal experimental techniques with mathematical modelling of MMTs ...
Downscale Finite Element Modeling of Aortic Valve Leaflets for In-Situ Estimation of Cell Level Mechanics
R. Buchanan, M. Sacks
Institute for Computational Engineering and Sciences, Department of Biomedical Engineering, University of Texas, Austin, TX, USA
As in all tissues, mechanical forces in the aortic valve (AV) modulate the constituent cell population’s physiology and biosynthetic activity. While advances have been made toward the understanding of this complex multi-scale relationship, the specific role that and extracellular matrix (ECM) coupling plays on the mechanical response of the AV interstitial cell (AVIC) is poorly understood. The ...
The Effects of the Electrical Double Layer on Giant Ionic Currents through Single Walled Carbon Nanotubes
G. Zhang[,][,], S.L. Bearden 
Department of Bioengineering, Clemson University, Clemson, SC, USA
Department of Electrical and Computer Engineering, Clemson University, Clemson, SC, USA
Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC, USA
Electrofluidic transport through a single walled carbon nanotube (SWCNT) is enhanced by electroosmosis. Electroosmosis is made possible in these devices by the combination of a large slip length within SWCNTs and the interfacial potential at the solution/nanotube interface. A computational model of a SWCNT device was developed using COMSOL Multiphysics to investigate the complete electrical ...
A. Warning, A. K. Datta
Department of Biological & Environmental Engineering, Cornell University, Ithaca, NY, USA
Predictive food microbiology currently first requires experimental data for growth on fresh produce and then fitting an empirical or semi-empirical model to the data, making extrapolation to other conditions (temperature, type of produce) difficult. Herein, we develop a mechanistic model for the growth of human pathogenic bacteria (Escherichia coli O157:H7 and Salmonella spp.) on spinach using ...
N. M. Sundaram, M. Sneha, A. Kandaswamy, R. Nithya
PSG College of Technology, Coimbatore, Tamil Nadu, India
Dr. N.G.P. Institute of Technology, Coimbatore, Tamil Nadu, India
The majority of elderly patients are subjected to hip bone replacement due to dislocation of bone, mechanical failure and infection. The life time of the implant varies from patient to patient depending on their daily physical activity. Once the implant fails, re-operation of hip bone replacement is performed. In United States, there are approximately 18 revision hip replacements performed for ...
T. Maguire [1,2], M. Davis , I. Marrero-Berrios , C. Zhu , C. Gaughan , J. Weinberg , D. Manchikalapati , J. SchianodiCola , R. S. Schloss , J. Yarmush , M. Yarmush ,
 Rutgers University, New Brunswick, NJ, USA
 BeauRidge Pharmaceuticals, New York, NY, USA
 Department of Anesthesiology, New York Methodist Hospital, Brooklyn, NY, USA
Introduction: While general anesthetics control pain via consciousness regulation, local anesthetics (LAs) act by decreasing sensation in the area of administration by blocking nerve transmission to pain centers. Perioperative intra-articular administration of LAs is a commonly employed procedure in orthopedic procedures to minimize patient surgical and post-surgical pain. LAs are also co ...
Numerical Simulations Demonstrate Safe Vitrification and Warming of Embryos Using the Rapid-i™ Device
B.O.J. Johansson, Y.A. Tarakanov, H.J. Lehmann, and S.P. Apell
Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden
Vitrolife Sweden AB, Västra Frölunda, Sweden
During cryopreservation of human embryos, ice crystal formation in the embryos or in surrounding media may cause cryodamage to them and can be lethal. A strategy to avoid this is the vitrification procedure when the embryo and the surrounding medium undergo the transition to glassy state rather than a crystalline one during cooling. Similarly, recrystallization in the embryo or the medium must ...
Simulation of a Magnetic Induction Method for Determining Passive Electrical Property Changes of Human Trunk Due to Vital Activities
H. Mahdavi, J. Rosell Ferrer
Universitat Politècnica de Catalunya, Barcelona, Spain
The human body consists of many different types of tissues each with specific passive electrical properties. Vital activities lead to a characteristic change of these properties and geometrical changes. Magnetic induction is a non-contact method which can be used to determine these changes. The method is based on the creation of a primary magnetic field that will produce eddy currents in the ...
Simulations of Heat and Mass Transport During Biomass Conversion Processes Using 3D Biomass Particle Models with Realistic Morphology and Resolved Microstructure - new
P. Ciesielski, M. Crowley, L. Thompson, B. Donohoe, D. Robichaud, A. Sanders, M. Nimlos, T. Foust
Biosciences Center, National Renewable Energy Laboratory, Golden, CO, USA
National Bioenergy Center, National Renewable Energy Laboratory, Golden, CO, USA
Quantum Electronics & Photonics Division, National Institute of Standards & Technology, Boulder, CO, USA
Predictive simulations of biomass conversion processes will improve their technical performance and reduce economic uncertainty surrounding industrialization of biofuels production. The majority of present conversion simulations treat the biomass feedstock with simplifying assumptions that neglect important characteristics that are unique to biomass particles. These characteristics, including ...