M. Cartas-Ayala, R. Karnik
Massachusetts Institute of Technology, Cambridge, MA, USA
Characterization of particles has numerous applications in science and diagnostics. Recently, particle passage through constrained microchannels has been proposed to characterize particles based on their passage velocity. Nevertheless, there is no clear understanding of how the physics in this system interact. Here we quantify the effects of the flow around the particle by simulating the passage ...
A. Lucantonio, P. Nardinocchi, L. Teresi
Università degli Studi La Sapienza, Roma, Italy
LaMS - Modelling & Simulation Lab, Università degli Studi Roma Tre, Roma, Italy
Polymer gels belong to the realm of soft active materials as they are capable of responding to a non-mechanical stimulus – the permeation of a solvent – with a mechanical action – a volume change, thanks to the coupling between different physics. This mechanism of coupling can be exploited in a wide range of applications, including biomedical devices, making crucial the understanding of the ...
X. Xu, T. Patel, R.W. Hoyt
U.S. Army Institute of Environmental Medicine, Natick, MA, USA
A human torso model was created for heat transfer analysis. The torso was derived from the ‘Virtual Family’ whole-body voxel data from the ITIS Foundation (Zurich, Switzerland). Measurements were taken from the ITIS male along the axial plane at key anatomical landmarks and used to develop geometry in Solidworks. Individual components were created to represent the skin, fat, muscle, and bone ...
I.M. Abdel-Motaleb, J. Lavrencik 
Department of Electrical Engineering, Northern Illinois University, DeKalb, IL, USA
There is urgent need to monitor dental and oral diseases, such as tooth decay, gum diseases, and teeth grinding. Such monitoring can be achieved by embedding sensors in the mouth. This technique faces some difficulties. The first is how the power needed for the operation of the sensors and the associated electronic chips can be generated. This power can be generated using the pressure exerted by ...
N. M. Sundaram, M. Sneha, A. Kandaswamy, R. Nithya
PSG College of Technology, Coimbatore, Tamil Nadu, India
Dr. N.G.P. Institute of Technology, Coimbatore, Tamil Nadu, India
The majority of elderly patients are subjected to hip bone replacement due to dislocation of bone, mechanical failure and infection. The life time of the implant varies from patient to patient depending on their daily physical activity. Once the implant fails, re-operation of hip bone replacement is performed. In United States, there are approximately 18 revision hip replacements performed for ...
N. P. Uth , J. Mueller , B. Smucker , A. Yousefi ,
 Department of Chemical, Paper, and Biomedical Engineering, Miami University, Oxford, OH, USA
 Research Computing Support, Miami University, Oxford, OH, USA
 Department of Statistics, Miami University, Oxford, OH, USA
Introduction: Bone tissue has a limited ability for regeneration; critically sized defects cannot self-heal and require medical intervention. Bone tissue engineering (TE) circumvents this issue by growing replacement bone tissue from the patient’s own cells inside scaffolds. TE scaffolds are porous constructs that act as a support structure during bone regeneration and helps cells attach and ...
A Multiscale-Multiphysics Model for Axon Pathfinding Simulation, the Example of the Olfactory System
G. Naldi, G. Aletti, P. Causin
Dipartimento di Matematica ‘F. Enriques’, Università degli Studi di Milano, Milano, Italy
In the developing embryo, neurons form connections by projecting axons to appropriate target areas. The projection process includes neurite elongation, resulting from the assembly of new cytoskeletal material at the free end of the axon, a complex cascade of steering decisions, driven by biomechanical properties of the surrounding environment and by signals in it. In this work we focus on the ...
Investigation of the Effect of Spinal Defects on Spondylolysis and Stress Fracture of Vertebral Bodies
M.S. Yeoman, C. Quah, A. Cizinauskas, K. Cooper, D. McNally, B. Boszczyk
Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
The Centre for Spinal Studies and Surgery, Queen’s Medical Centre, Nottingham, United Kingdom
Bioengineering Research Group, Faculty of Engineering, The University of Nottingham, Nottingham, United Kingdom
Spondylolysis (SL) is a defect of the spinal vertebra, and is typically caused by stress fracture of the pars interarticularis bone of the vertebral arch. It is especially common in adolescents who over train in sporting activities. Spina bifida occulta (SBO) is a malformation of the spine where the protruding vertebral bodies are not fully formed. In this study we demonstrate the predisposition ...
G. Megali, D. Pellicanò, M. Cacciola, F. Calarco, D. De Carlo, F. Laganà, and F.C. Morabito
DIMET Department, Faculty of Engineering, University “Mediterranea” of Reggio Calabria, Reggio Calabria, Italy
Constitutive properties of living cells are able to withstand physiological environment as well as mechanical stimuli occurring within and outside the body. We examined fluid flow and Neo-Hookean deformation related to the rolling effect. A mechanical model to describe the cellular adhesion with detachment is here proposed. We developed a finite element analysis, simulating blood cells attached ...
A. Gizzi, C. Cherubini, S. Migliori, and S. Filippi
Nonlinear Physics and Mathematical Modeling Lab, Engineering Faculty, University Campus Bio-Medico, Roma, Italy
International Center for Relativistic Astrophysics, University of Rome La Sapienza, Roma, Italy
Alberto Sordi Foundation, Research Institute on Aging, Roma, Italy
Postoperative or paralytic Ileus (PI) is a temporary aftermath of major abdominal surgeries. PI prevents the passage of food throughout the lumen leading to bloating, distension, emesis and pain. A plausible mathematical model for this phenomenology physiologically fine tuned including thermal variations, is presented here. Using COMSOL Multiphysics the existing intestinal ionic model have been ...