COMSOL Conference 2013

Bioscience and Bioengineering

Bioscience and bioengineering applications such as bone mechanics, cellular response to applied electric fields, and implantable biosensors were investigated using multiphysics simulation. Read the papers, posters, and presentations on this page to learn more about these applications in addition to many others that were presented at the COMSOL Conference.

A Multiphase Porous Medium Transport Model with Distributed Sublimation Front to Simulate Vacuum Freeze Drying

A. Warning, J. M. R. Arquiza, A. K. Datta

Cornell University, Ithaca, NY, USA

Coupled PDEs with Initial Solution from Data in COMSOL Multiphysics®

M. K. Gobbert, X. Huang, S. Khuvis, S. Askarian, B. E. Peercy

University of Maryland - Baltimore County, Baltimore, MD, USA

A Practical Method to Model Complex Three-Dimensional Geometries with Non-Uniform Material Properties Using Image-based Design and COMSOL Multiphysics®

J. Cepeda1, S. Birla2, J. Subbiah2, H. Thippareddi1

1Department of Food Science & Technology, University of Nebraska, Lincoln, NE, USA
2Department of Biological Systems Engineering, University of Nebraska, Lincoln, NE, USA

Feed-forward/Feed-backward Mechanical Amplification in the Mouse Cochlea

J. Soons1,2, C. Steele2, S. Puria2

1Lab of Biomedical physics, University of Antwerp, Antwerp, Belgium
2Department of Mechanical Engineering, Stanford University, Stanford, USA

Acoustic Field Comparison of High Intensity Focused Ultrasound Using Experimental Characterization and Finite Element Simulation

J. L. Teja, A. Vera, L. Leija

Department of Electrical Engineering, Cinvestav-IPN, Mexico D.F., Mexico

Heat Transfer and Phase Transformation on Matrix Assisted Pulsed Laser Evaporation (MAPLE) of Biocompatible Thin Layers

E. Lacatus1, G.C. Alecu1, M.A. Sopronyi2, A. Tudor1

1POLITEHNICA University of Bucharest, Bucharest, Romania
2INFLPR -National Institute for Laser Plasma and Radiation Physics, Bucharest, Romania

Determination of Mechanic Resistance of Osseous Element Through Finite Element Modeling

E. Isaza, E. Salazar, L. Florez

Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia

Modeling Deep-Bed Grain Drying Using COMSOL Multiphysics®

J.G. Pieters, R. ElGamal, F. Ronsse

Faculty of Bioscience Engineering, Department of Biosystems Engineering, Ghent, Belgium

Effect of Electrical Field Distortion on Particle-Particle Interaction Under DEP

G. Zhang1, Y. Zhao1, J. Hodge1, J. Brcka2, J. Faguet2, E. Lee2

1Clemson University, Clemson, SC, USA
2TEL U.S. Holdings, Inc., U.S. Technology Development Center, Austin, TX, USA

Alternate Glucometer Bio-sensor Model based on Ultrasonic MEMS Transceivers

P. Pattnaik1, S. K. Kamilla 1, Debi Prasad Das2

1MEMS Design Center, Institute of Technical Education & Research (ITER),Siksha ‘O’ Anushandhan University, Bhubaneswar-751030, Odisha,India
2Process Engineering and Instrumentation Cell,Institute of Minerals and Materials Technology (IMMT),Bhubaneswar, Odisha,India

Modeling Drug Release from Materials Based on Electrospun Nanofibers

P. Nakielski, T. Kowalczyk, T.A. Kowalewski

Institute of Fundamental Technological Research Polish Academy of Sciences, Warsaw, Poland

Electrohydrodynamic Micropump Modeling for Performance Optimization

A. Mulye1, S. Potnis2

1Northeastern University, Boston, MA, USA
2VIT, Mumbai, Maharashtra, India

Comparing Isotropic and Anisotropic Brain Conductivity Modeling: Planning Optimal Depth-Electrode Placement in White Matter for Direct Stimulation Therapy in an Epileptic Circuit

L. C. Zaragoza1, B. Hondorp2, M. A. Rossi3

1ITESM, Monterrey, Mexico
2Rush Medical College, Chicago, IL, USA
3Rush University Medical Center, Chicago, IL, USA

Modeling 3D Calcium Waves from Stochastic Calcium Sparks in a Sarcomere Using COMSOL Multiphysics®

L. T. Izu1, Z. Coulibaly2, B. Peercy2

1University of California-Davis, Davis, CA, USA
2University of Maryland, Catonsville, MD, USA

Application of the Focused Impedance Method (FIM) to Determine the Volume of an Object within a Volume Conductor

M. A. Kadir1, S. P. Ahmed2, G. D. Al Quaderi3, R. Rahman2, K. Siddique-e Rabbani1

1Department of Biomedical Physics & Technology, University of Dhaka, Dhaka, Bangladesh
2Department of Physics, Jahangirnagar University, Savar, Dhaka, Bangladesh
3Department of Physics, University of Dhaka, Dhaka, Bangladesh

A Finite Element Model of Shear Wave Propagation Induced by an Acoustic Radiation Force Impulse

R. De Luca1,2, J. Fromageau1, H.W. Chan1, F. Marinozzi2, J. Bamber1

1Institute of Cancer Research and Royal Marsden Hospital, Sutton, England, United Kingdom
2Sapienza University of Rome, Dept. of Mechanical and Aerospace Engineering, Rome, Italy

A Comparison Between an A-V and V Formulation in Transcranial Magnetic Stimulation

B. Granula1, K. Porzig2, H. Toepfer2, M. Gacanovic1

1University of Banja Luka, Banja Luka, Bosnia-Herzegovina
2Technische Universität Ilmenau, Ilmenau, Germany

Finite Element Analysis of Defibrillation Current Density in Pregnant Women

A. Jeremic, E. Khosrowshahli

McMaster University, Hamilton, ON, Canada

Actively Controlled Ionic Current Gating In Nanopores

G. Zhang, S. Bearden

Clemson University, Clemson, SC, USA

Understanding the Role of Nanomaterials in DNA Biosensors Through Finite Element Analysis

J. C. Kumaradas1, A. Zhang2, Y. D. Davletshin1

1Ryerson University, Toronto, ON, Canada
2University of Waterloo, Waterloo, ON, Canada

Electrical Characterization of Biological Cells on Porous Substrate Using COMSOL Multiphysics®

D. Mondal, C. RoyChaudhuri

Department of Electronics and Telecommunication Engineering, Bengal Engineering and Science University, Howrah, West Bengal, India

Flow-induced Vibrations of the Uvula and its Implication on Snoring

J. Xi, Q. M. Mohamad, Y. E. Yuan, J. Rohlinger

Mechanical and Biomedical Engineering, Central Michigan University, Mount Pleasant, MI, USA

Simulation of the Electrode-Tissue Interface with Biphasic Pulse Train for Epi-retinal Prosthesis

S. Biswas1, S. Das2, M. Mahadevappa2

1Advanced Technology Development Center, Indian Institute of Technology, Kharagpur
2School of Medical Science and Technology, Indian Institute of Technology, Kharagpur

Simulating Organogenesis in COMSOL Multiphysics®: Parameter Optimization for PDE-based Models

D. Iber1, D. Menshykau2, P. Germann2, L. Lermuzeaux2,3

1D-BSSE, ETH Zurich, Switzerland, SIB, Basel, Switzerland
2D-BSSE, ETH Zurich, Basel, Switzerland
3Department of Bioengineering, University of Nice-Sophia Antipolis, Nice, France

Modeling Light Propagation in Skin for Visualization of Subcutaneous Veins

H. Kwon, R. Huancaya

Andrews University, Berrien Springs, MI, USA

Singlet Oxygen Modeling for PDT Incorporating Local Vascular Oxygen Diffusion

T. C. Zhu, B. Liu

University of Pennsylvania, Philadelphia, PA, USA

Some Commonly Neglected Issues Which Affect DEP Applications

G. Zhang1, V. Pandian1, J. Brcka2, J. Faguet2, E. Lee2

1Clemson University, Clemson, SC, USA
2TEL U.S. Holdings, Inc., U.S. Technology Development Center, Austin, TX, USA

Wireless Power and Communications for Implantable Biosensors

C. Romero, M. Mujeeb-U-Rahman

California Institute of Technology, Pasadena, CA, USA

A Model of Noninvasive Radiofrequency Tissue Heating

L. Rems, D. Miklavcic

University of Ljubljana, Faculty of Electrical Engineering, Ljubljana, Slovenia

Simulation of Transdermal Toxin Expulsion via Adsorptive Dermal Patch using COMSOL Multiphysics®

H. Kwon, M. Hess II, R. M. Polski

Andrews University, Berrien Springs, MI, USA

Effects of Flow and Diffusion on Blood Coagulation in Platelet Poor Plasma: a Two-way Coupling Between Hemodynamics and Biochemistry

D. Magnabosco1,2, H. van Ooijen2, B. Bakker2, R. van den Ham2

1Politecnico di Milano, Milan, Italy
2Philips Research, Eindhoven, The Netherlands

Computational design and analysis of Microwave Tomography in Intracerebral Hemorrhage

Priyadarshini Natarajan , Rajkumar ElagiriRamalingam

Division of Biomedical Engineering, School of Biosciences and Technology, VIT University, Tamil Nadu, India

An Assessment of the Suitability of the Body and Adult Head Coils for Transmission during Paediatric Magnetic Resonance Imaging

G.R. Cook1, M.J. Graves1, F.J. Robb2, D.J. Lomas1

1Department of Radiology, University of Cambridge, Cambridge, United Kingdom
2General Electric Healthcare Coils, Aurora, Ohio, USA

Computational Analysis on Commercially Available Stent Designs

K. Basu1, P. Ghosh2, S. Bhattacharjee2, S. Das 2, A. Chanda1

1School of Bio Science and Engineering, Jadavpur University, Kolkata, West Bengal, India
2Department of Mechanical Engineering, Jadavpur University, Kolkata, West Bengal, India

Elucidating the Mechanism Governing the Cell Rotation Behavior Under DEP

G. Zhang1, Y. Zhao1, J. Brcka2, J. Faguet2, E. Lee2

1Clemson University, Clemson, SC, USA
2TEL U.S. Holdings, Inc., U.S. Technology Development Center, Austin, TX, USA

Modelling the Response of Microdialysis Probes in Glucose Concentration Measurement

J.M. Gozálvez-Zafrilla1, A. Santafé-Moros1, J.L. Díez-Ruano2, J. Bondia2

1Institute for Industrial, Radiophysical and Environmental Safety (ISIRYM) - Universitat Politècnica de Valencia, Valencia, Spain
2Instituto Universitario de Automática e Informática Industrial (AI2) - Universitat Politècnica de Valencia, Valencia, Spain

Multiphysics Modeling and Analysis of DBS Electrodes: Application to Parkinson’s Disease

M.Vidya, M. SharatDivya, N.Priyadarshini, E.R Rajkumar

Division of Biomedical Engineering, Center for Biomedical Engineering Research, School Of Biosciences and Technology, VIT University Vellore, India.

Development of a Multiphase, Multispecies Droplet Evaporation Model for Optimization of Desiccation Preservation Techniques

A. Sinkevich, S. Bhowmick , M. Raessi

University of Massachusetts Dartmouth, North Dartmouth, MA, USA

Modeling Phytoremediation by Mangroves

O. Richter1, H. Anh Nguyen1, V. Phuoc Nguyen2

1Institute of Geoecology, University of Technology Braunschweig, Germany
2Institute for Environment & Resources, HCM-City, Vietnam

Shear Stress Analysis in High-Throughput Dual-micropillar-based Microfluidic Platform

J.Borana1, J.M.Lee2, B.G.Chung2

1Indian Institute of Technology Guwahati, Guwahati, India
2Department of Mechanical Engineering, Sogang University, Seoul, Korea

Deformable Image Registration for Pleural Photodynamic Therapy

B. Liu, T. C. Zhu

Department of Radiation Oncology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

Hemodynamic Simulations of Implanted Multilayer Flow Modulator

A.B. Boubker, A. Restante

CARDIATIS, Isnes, Belgium

In Silico Evaluation of Local Hemodynamics Following Vena Cava Filter Deployment

J. Ferdous1, M. Ghaly 2, V. B. Kolachalama 3, T. Shazly1,4

1Biomedical Engineering Program, University of South Carolina, Columbia, SC, USA
2Department of Biomedical Engineering, North Carolina State University, Raleigh, NC, USA
3Charles Stark Draper Laboratory, Cambridge, MA, USA
4Department of Mechanical Engineering, University of South Carolina, Columbia, SC, USA

Pushability Model of a Microcatheter for Intravascular Procedures

M. Miliani, F. Piccagli

Medtronic Invatec S.p.A., Roncadelle, BS, Italy

Can Oscillatory Convection Accelerate Signal Propagation in Simple Epithelium?

M. Nebyla, M. Pribyl

Institute of Chemical Technology, Prague, Department of Chemical Engineering, Prague, Czech Republic

Optimization of 3D Layered Metal-Dielectric Stacks (MDS) for Near-Field Fluorescence Imaging

P.S. Tan1, K. Elsayad2, K. Heinze1

1Rudolf Virchow Center, University of Würzburg, Würzburg, Germany
2Research Institute of Molecular Pathology (IMP), Vienna, Austria

Multiphysics Modelling and Simulation of Implantable Wireless MEMS Capacitive Sensor for Cardiovascular Diagnostics

R.Yogeswari, S.Venkateshwaran , K.Umapathi

United Institute of Technology,Coimbatore,Tamil Nadu, India

Simulating Organogenesis in COMSOL Multiphysics®: Cell-based Signaling Models

D. Iber, J. Vollmer, D. Menshykau

Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland

Generation of Lofted NURBS Curves for 3D Model Generation with COMSOL Multiphysics®

R.T. Hart

Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA

COMSOL Multiphysics® Model of Canine Elbow for Use in Investigating Medial Coronoid Disease

K. A. Bodnyk1, G. J. Noble1, N. Fitzpatrick2, M. J. Allen3, K. Stephenoff1, R. T. Hart1

1Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA
2Fitzpatrick Referrals, Godalming, Surrey, United Kingdom
3Department of Veterinary Medicine, The Ohio State University, Columbus, OH, USA

Modeling of an Oxygenation-Aided 3D Culture for Functional Beta-Cell Expansion

S. Jin1, J. McReynolds1, X. Li2, J. Guan2

1Department of Biomedical Engineering, College of Engineering, University of Arkansas, Fayetteville, AR, USA
2Department of Materials Science and Engineering, The Ohio State University, Columbus, OH, USA

Simulating Thermotherapeutic Response Induced by Thermal Padding for Treating Acute Injuries

J. Kantor, Y. Feng, C. Acosta, E. Massingill

University of Texas at San Antonio, San Antonio, TX, USA

Electrical Response and Thermal Damage Assessment of Cutaneous and Subcutaneous Tissues to Noninvasive Radiofrequency Heating: A Computational Modeling Study

A. González-Suárez[1,2], J. N. Jimenez-Lozano[3], W. Franco

1Wellman Center for Photomedicine, Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA
2Biomedical Synergy, Electronic Engineering Department, Universitat Politècnica de València, Valencia, Spain
3ZELTIQ Aesthetics, Inc., Pleasanton, CA, USA

Modeling Inertial Focusing in Straight and Curved Microfluidic Channels

J. Martel1, N. Elabbasi2, D. Quinn2, J. Bergstrom2, M. Toner1

1BioMEMS Resource Center, Massachusetts General Hospital, Boston, MA, USA
2Veryst Engineering, Needham, MA, USA

Cellular Scale Model of Stratum Corneum

R. Santoprete, B. Querleux

L'Oréal, Paris, France

Modeling Plant Morphodynamics in Predefined COMSOL Multiphysics® Interface

S. Nikolaev1, A. Trubuil2

1Institute of cytology and genetics SB RAS, Novosibirsk, Russia
2Institut National de la Recherche Agronomique, Jouy-en-Josas, France

ISBN: 978-0-9910001-5-9
ISSN: 2372-2215